6-Fluoro-2-oxo-2H-chromene-3-carboxylic acid
CAS: 937688-27-2
Ref. 3D-MMB68827
| 25mg | 211.00 € | ||
| 250mg | 841.00 € |
Product Information
6-Fluoro-2-oxo-2H-chromene-3-carboxylic acid is a fluorescent molecule that has been used as a probe for cancer cells. It can be used to detect the presence of lung cancer cells by binding to a protein called Vegf, which is expressed in these cells. In mice with xenografts of human lung cancer cells, 6-fluoro-2-oxo-2H-chromene 3 carboxylic acid (6FO) was injected intravenously and taken up by the tumor. The 6FO was then detected using fluorescence imaging techniques and shown to have anti tumor effects. 6FO also binds to tyrosine kinase receptors on the surface of cancer cells, inhibiting cell growth, and shows anti angiogenic properties by blocking the migration of blood lymphocytes.
Chemical properties
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