N-(Phenyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside
Ref. 3D-MP08504
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Product Information
N-(Phenyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside (NPG) is a synthetic oligosaccharide. It is an Methylation and Click modification of the natural glycosylation product of glucose with pivalic acid. NPG has been shown to inhibit the Glycosylation enzyme by methylating it and preventing it to be able to catalyze the attachment of a sugar molecule to an amino acid residue. This inhibition prevents the production of complex carbohydrates in bacteria. NPG is also fluorinated at the 2,3,4,6 positions on the glucose ring which allows for better binding to bacterial cells. NPG has been shown to bind specifically to mycobacterial cell wall glycolipids and inhibit their synthesis as well as other bacterial cells such as staphylococcus aureus.
Chemical properties
Technical inquiry about: 3D-MP08504 N-(Phenyl-1-propenyl)imino-2,3,4,6-tetra-O-pivaloyl-D-glucopyranoside
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