2,3,5-Tri-O-benzyl-1-a-D-arabinofuranosyl chloride

CAS: 4060-34-8

Ref. 3D-MT71647

Product Information

• Name: 2,3,5-Tri-O-benzyl-1-a-D-arabinofuranosyl chloride
• Synonyms: Arabinofuranosylchloride, 2,3,5-tri-O-benzyl-, a-D- (8CI), 2,3,5-Tri-O-benzyl-a-D-arabinofuranosyl chloride

Description

2,3,5-Tri-O-benzyl-1-a-D-arabinofuranosyl chloride is a patent antibiotic produced by Streptomyces antibioticus. It has potent anticancer activity and is being developed as an antitumor agent. 2,3,5-Tri-O-benzyl-1-a-D-arabinofuranosyl chloride inhibits cell proliferation by inhibiting DNA synthesis and protein synthesis. This compound also induces programmed cell death (apoptosis) in tumor cells. Vidarabine is a nucleoside analog that can be used to treat herpes virus infections of the eye or genital tract. Vidarabine is chemically synthesized from 2,3,5 tri O benzyl d arabinofuranosyl chloride and has been shown to have potential antitumor activity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 438.94 g/mol
• Formula: C₂₆H₂₇ClO₄
• Purity: Min. 95%
• InChI: InChI=1S/C26H27ClO4/c27-26-25(30-18-22-14-8-3-9-15-22)24(29-17-21-12-6-2-7-13-21)23(31-26)19-28-16-20-10-4-1-5-11-20/h1-15,23-26H,16-19H2/t23-,24-,25+,26+/m1/s1
• InChI key: InChIKey=YBBDIXWREGHZRM-XPGKHFPBSA-N
• SMILES: Cl[C@H]1O[C@H](COCc2ccccc2)[C@@H](OCc2ccccc2)[C@@H]1OCc1ccccc1