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8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine
CAS: 142784-25-6
Ref. 3D-NA04649
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire |
Product Information
- N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridineN-(D-Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5 -b]pyridine
- 2'-Deoxy-8-[(1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridin-2-yl)amino]guanosine
- N-(Deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-]pyridine
8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine (8-APdG) is a mutagen that induces genotoxic effects and mutations in mammalian cells. It has been shown to react with DNA to form covalent complexes and induce point mutations or transversions. 8-APdG has been found in the environment as a result of environmental pollution by polycyclic aromatic hydrocarbons and tobacco smoke. 8-APdG also induces genetic damage in human lymphoblastoid cells in vitro, including mutations at the HPRT locus.
Chemical properties
Technical inquiry about: 3D-NA04649 8-(2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridyl)-2'-deoxyguanosine
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