3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt

CAS: 133525-01-6

Ref. 3D-NA06316

Product Information

• Name: 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt
• Synonyms: AZT GlucuronideZidovudine glucuronide sodium salt
• Brand: Biosynth
• Description: 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt is an antiviral and anticancer agent that inhibits the synthesis of DNA, RNA, and protein. It has shown to be effective against a variety of viruses including HIV-1, herpes simplex virus type 1, influenza A virus, vaccinia virus, and vesicular stomatitis virus. 3'-Azido-3'-deoxythymidine-b-D-glucuronide sodium salt also inhibits the growth of cancer cells in vitro. This drug is a modified nucleoside with a phosphoramidite backbone and a 3'-azido group at one end. The other end contains a beta D glucuronic acid moiety. The modifications allow for the inhibition of DNA synthesis by blocking the incorporation of deoxyribonucleotides into DNA chains.

Chemical properties

• Molecular weight: 465.35 g/mol
• Formula: C₁₆H₂₀N₅NaO₁₀
• Purity: Min. 95%
• Color/Form: Powder