Product Information
- 2-Amino-8-D-ribofuranosyl-imidazol[1,2-a]-1,3,5-triazin-4(8H)-one
5-Aza-7-deazaguanosine is a nucleoside analogue that has antiviral activity against herpes simplex virus, influenza, and other DNA viruses. 5-Aza-7-deazaguanosine is an analog of guanosine with the addition of a 7-deaza group on the nitrogen atom. This drug inhibits viral replication by inhibiting the polymerase function of the viral NS5B protein, which is essential for DNA synthesis. The structure activity relationship studies have shown that this compound has anti-hepatitis B virus activity, but not against hepatitis C virus. 5-Aza-7-deazaguanosine has been shown to be effective in animal models as well as in humans without any significant toxicity issues.
Chemical properties
Technical inquiry about: 3D-NA09785 5-Aza-7-deazaguanosine
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