5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide

CAS: 23274-21-7

Ref. 3D-NA11364

Product Information

• Name: 5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide

Description

5-Amino-1-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-imidazole-4-carboxamide (AICAR) is a high purity novel nucleotide analog that has been shown to be an activator of AMPK. AICAR can act as a substitute for ATP, the molecule that drives cellular energy production. AICAR has been shown to inhibit tumor growth and induce apoptosis in cancer cells. This compound also inhibits viral RNA replication by competitively binding to the enzyme polymerase, which is essential for viral replication.

• Brand: Biosynth

Chemical properties

• Molecular weight: 384.34 g/mol
• Formula: C₁₅H₂₀N₄O₈
• Purity: Min. 95%
• InChI: InChI=1S/C15H20N4O8/c1-6(20)24-4-9-11(25-7(2)21)12(26-8(3)22)15(27-9)19-5-18-10(13(19)16)14(17)23/h5,9,11-12,15H,4,16H2,1-3H3,(H2,17,23)
• InChI key: InChIKey=ZGVQACKXOOWCLS-UHFFFAOYSA-N
• SMILES: CC(=O)OCC1OC(n2cnc(C(N)=O)c2N)C(OC(C)=O)C1OC(C)=O