5-Aminouridine

CAS: 2149-76-0

Ref. 3D-NA163143

Product Information

• Name: 5-Aminouridine
• Synonyms: 5-amino-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• CAS: 2149-76-0

Description

5-Aminouridine is an analog of uridine that is used in the synthesis of RNA. It inhibits the synthesis of RNA by viruses, and it may also inhibit the synthesis of RNA by cells, including muscle cells. 5-Aminouridine has been shown to inhibit protein synthesis in muscle cells incubated with orotic acid. The drug may also interact with other drugs metabolized by UDP-glucose pyrophosphorylase, such as carbamazepine and phenytoin. This interaction may lead to decreased serum levels of these drugs following treatment with 5-aminouridine.

• Brand: Biosynth

Chemical properties

• Molecular weight: 259.22 g/mol
• Formula: C₉H₁₃N₃O₆
• Purity: Min. 90 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C9H13N3O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2,10H2,(H,11,16,17)
• InChI key: InChIKey=YBTWWWIJBCCYNR-UHFFFAOYSA-N
• SMILES: Nc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O