5'-Azido-2',5'-dideoxycytidine
CAS: 4803-88-7
Ref. 3D-NA45440
| 2mg | 128.00 € | ||
| 5mg | 184.00 € | ||
| 10mg | 287.00 € | ||
| 25mg | 431.00 € | ||
| 50mg | 576.00 € |
Product Information
5'-Azido-2',5'-dideoxycytidine is a macrocyclic nucleoside that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. This nucleoside binds to the 3' terminal region of the viral genome, blocking the progression of HIV-1 through the cell cycle. 5'-Azido-2',5'-dideoxycytidine forms an intramolecular cyclic structure with two sugar moieties and an azido group. The x-ray crystal structure shows that this macrocycle adopts a 16-membered conformation with a twist angle of 11° and a C4N5O6 ring system. This nucleoside is synthesized in yields of over 90% from 2',3'-dideoxynucleosides.
Chemical properties
Technical inquiry about: 3D-NA45440 5'-Azido-2',5'-dideoxycytidine
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