2-Amino-4-(4-methoxyphenyl)pyrimidine

CAS: 99844-02-7

Ref. 3D-NA57406

Product Information

• Name: 2-Amino-4-(4-methoxyphenyl)pyrimidine
• Synonyms: 4-(4-Methoxyphenyl)pyrimidin-2-amine, 2-Pyrimidinamine, 4-(4-Methoxyphenyl)-, 4-(4-Methoxyphenyl)Pyrimidin-2-Amine, 4-amino-4-(4-Methoxyphenyl)-Pyrimidine

Description

2-Amino-4-(4-methoxyphenyl)pyrimidine (AMP) is a synthetic nucleoside analog. It has antiviral activity and is used for the treatment of hepatitis B virus infection. AMP inhibits viral DNA polymerase and prevents the synthesis of viral DNA and RNA. It has been modified to include a methoxy group at the 4 position, which provides additional stability against the enzyme ribonuclease. AMP is also an activator of ribonucleotide reductase and can be used as a substrate to synthesize deoxyribonucleosides, phosphoramidites, diphosphate, or monophosphate nucleotides for DNA synthesis.
AMP has CAS number 99844-02-7 and is available in high purity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 201.22 g/mol
• Formula: C₁₁H₁₁N₃O
• Purity: Min. 95%
• InChI: InChI=1S/C11H11N3O/c1-15-9-4-2-8(3-5-9)10-6-7-13-11(12)14-10/h2-7H,1H3,(H2,12,13,14)
• InChI key: InChIKey=GHSMJZASRNAUBJ-UHFFFAOYSA-N
• SMILES: COc1ccc(-c2ccnc(N)n2)cc1