4-Amino-2,6-dihydroxy-5-nitrosopyrimidine

CAS: 5442-24-0

Ref. 3D-NA70257

Product Information

• Name: 4-Amino-2,6-dihydroxy-5-nitrosopyrimidine
• Synonyms: 2,4(1H,3H)-Pyrimidinedione, 6-amino-5-nitroso-, 4-Amino-5-nitroso-2,6-pyrimidinediol, 5-Nitroso-6-aminouracil, 6-Amino-5-nitroso-2,4(1H,3H)-pyrimidinedione, 6-Amino-5-nitroso-2,4-pyrimidinediol, 6-Amino-5-nitroso-22,4(1H,3H)-pyrimidinedione, 6-Amino-5-nitrosouracil, NSC 11446, NSC 14287, NSC 3101, NSC 677501, NSC 94946, Uracil, 6-amino-5-nitroso-

Description

4-Amino-2,6-dihydroxy-5-nitrosopyrimidine is a molecule that has been shown to be an effective inhibitor of the enzyme tyrosinase in the oxidation of tyrosine to DOPA, which is a precursor of melanin. It is believed that vibrational and structural changes during these reactions are responsible for the inhibitory effects. 4-Amino-2,6-dihydroxy-5-nitrosopyrimidine has also been shown to have anti cancer effects on glioma cells. This molecule binds to copper ions, forming a chelate ring that can stabilize reactive intermediates and terminate free radicals. The chlorine atom on this molecule may be responsible for its cytotoxic effects by reacting with nucleophilic sites on proteins. The functional groups on this molecule react with acid catalysts, such as protonation or dehydration reactions.

• Brand: Biosynth

Chemical properties

• Molecular weight: 156.1 g/mol
• Formula: C₄H₄N₄O₃
• Purity: Min. 98 Area-%
• Color/Form: Powder