4-Pyridinecarboxylic acid, 3-ethyl-, methyl ester
CAS: 13341-16-7
Ref. 3D-NAA34116
1g | 949.00 € | ||
100mg | 239.00 € |
Product Information
4-Pyridinecarboxylic acid, 3-ethyl-, methyl ester (PCME) is a synthetic chemical compound that belongs to the group of indole alkaloids. It is used as a precursor in the synthesis of dasycarpidone, an anti-inflammatory drug. PCME is synthesised by the dehydrogenation of 4-(3-ethoxycarbonyl-4-pyridinyl)-2-butanone (1). Protonation of PCM yields the enamine 2 and subsequent reaction with chloroacetyl chloride leads to the desired product. The synthesis of PCME can be described as follows:
Step 1: 4-(3-ethoxycarbonyl-4-pyridinyl)-2-butanone (1) is reacted with sodium methoxide in methanol to yield 4-(3-ethoxycarbonylmethylene)-2-(methylthio)butanal (2
Chemical properties
Technical inquiry about: 3D-NAA34116 4-Pyridinecarboxylic acid, 3-ethyl-, methyl ester
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