Product Information
- 1-(5,5-Dioxido-10H-phenothiazin-10-yl)-N,N-dimethylpropan-2-amine
- 1-(5,5-Dioxophenothiazin-10-yl)-N,N-dimethylpropan-2-amine
- 10H-Phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide (9CI)
- 10H-Phenothiazine-10-ethanamine, N,N,α-trimethyl-, 5,5-dioxide
- 10H-phenothiazine-10-ethanamine, N,N,alpha-trimethyl-, 5,5-dioxide
- 9,9-Dioxopromethazine
- 9,9-Dioxypromethazin
- Dioxopromethazine
- Phenothiazine, 10-[2-(dimethylamino)propyl]-, 5,5-dioxide
- Promethazine 5,5-dioxide
- See more synonyms
- Prothanon
Promethazine is an antihistamine used to treat the symptoms of allergies and the common cold. Promethazine Sulfone is a metabolite of promethazine that has been shown to be responsible for its anti-inflammatory effect. It also has strong binding constants with human serum albumin, which may be due to hydrogen bonding interactions. Promethazine Sulfone is excreted mainly in urine as a result of metabolism by CYP2D6, which converts it into promethazine. Promethazine Sulfone inhibits chemiluminescence in a photomultiplier tube at a pH below 6.8 and hydrolysis by hydrochloric acid, but not at pH 7 or above.
Chemical properties
Technical inquiry about: 3D-NAA75456 Promethazine Sulfone
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