Rifampicin quinone
CAS: 13983-13-6
Ref. 3D-NAA98313
| 1mg | 53.00 € | ||
| 2mg | 85.00 € | ||
| 5mg | 118.00 € | ||
| 10mg | 189.00 € | ||
| 25mg | 277.00 € |
Product Information
Rifampicin is a quinone that is used as an antibiotic. It is the most active of the rifamycins for the treatment of tuberculosis. Rifampicin has been shown to have a redox cycle and may be involved in transfer reactions with other biomolecules, such as tenofovir alafenamide hemifumarate (TAF), which is used in HIV therapy. Rifampicin binds to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Rifampicin also specifically binds to markers expressed at high levels
Chemical properties
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