5-Bromo-2,4-di(benzyloxy)pyrimidine

CAS: 41244-53-5

Ref. 3D-NB57419

Product Information

• Name: 5-Bromo-2,4-di(benzyloxy)pyrimidine
• Synonyms: 2,4-Bis(benzyloxy)-5-bromopyrimidine, Pyrimidine, 5-bromo-2,4-bis(phenylmethoxy)-

Description

5-Bromo-2,4-di(benzyloxy)pyrimidine is an activator of DNA and RNA synthesis. It is a phosphoramidite that is used in the synthesis of oligonucleotides. 5-Bromo-2,4-di(benzyloxy)pyrimidine has antiviral activity and can inhibit the replication of HIV in vitro. This compound also has anticancer activity when it is given as a monophosphate, while its diphosphate form inhibits DNA and RNA synthesis. 5-Bromo-2,4-di(benzyloxy)pyrimidine can be synthesized from 2,4-dibenzyloxy pyrimidine and bromine in high purity with a CAS number 41244-53-5.

• Brand: Biosynth

Chemical properties

• Molecular weight: 371.23 g/mol
• Formula: C₁₈H₁₅BrN₂O₂
• Purity: Min. 95%
• InChI: InChI=1S/C18H15BrN2O2/c19-16-11-20-18(23-13-15-9-5-2-6-10-15)21-17(16)22-12-14-7-3-1-4-8-14/h1-11H,12-13H2
• InChI key: InChIKey=QMPWETJGPVPWGU-UHFFFAOYSA-N
• SMILES: Brc1cnc(OCc2ccccc2)nc1OCc1ccccc1