6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine

CAS: 16754-79-3

Ref. 3D-NC06328

Product Information

• Name: 6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine
• Synonyms: 6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

Description

6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a monophosphate nucleoside analog that is used as an antiviral agent. It is a synthetic compound that is activated by phosphorylation to form the triphosphate, which inhibits viral DNA synthesis by binding to the RNA polymerase enzyme. 6-Chloro-7-deaza-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine has been shown to be effective against cancer cells in vitro and in vivo and may be useful for the treatment of human immunodeficiency virus (HIV).

• Brand: Biosynth

Chemical properties

• Molecular weight: 411.79 g/mol
• Formula: C₁₇H₁₈ClN₃O₇
• Purity: Min. 97 Area-%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C17H18ClN3O7/c1-8(22)25-6-12-13(26-9(2)23)14(27-10(3)24)17(28-12)21-5-4-11-15(18)19-7-20-16(11)21/h4-5,7,12-14,17H,6H2,1-3H3/t12-,13-,14-,17?/m1/s1
• InChI key: InChIKey=RSIFXHMDLADHFU-OMNQEHGGSA-N
• SMILES: CC(=O)OC[C@H]1OC(n2ccc3c(Cl)ncnc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O