8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt
CAS: 93882-12-3
Ref. 3D-NC10429
| 10mg | 188.00 € | ||
| 25mg | 353.00 € | ||
| 50mg | 469.00 € | ||
| 100mg | 627.00 € | ||
| 250mg | 900.00 € |
Product Information
- pCPT-cAMP
- 4H-Furo[3,2-d]-1,3,2-dioxaphosphorin, adenosine deriv.
- 8-(p-Chlorophenylthio)-cAMP sodium salt
- Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), monosodium salt
- Adenosine, 8-[(4-chlorophenyl)thio]-, cyclic 3′,5′-(hydrogen phosphate), sodium salt (1:1)
- sodium (4aR,6R,7R,7aS)-6-{6-amino-8-[(4-chlorophenyl)sulfanyl]-9H-purin-9-yl}-7-hydroxytetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-2-olate 2-oxide
8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt (8-CPT-cAMP) is a cytosolic second messenger that regulates physiological processes. It interacts with the G protein coupled receptor 2-adrenergic receptor, and activates adenylyl cyclase to produce cAMP. 8-CPT-cAMP also induces mitochondrial membrane potential depolarization and Ca2+ release from the endoplasmic reticulum, which leads to cell death. The pro-apoptotic protein Bax is upregulated by 8-CPT-cAMP in cells and contributes to cell death.
Chemical properties
Technical inquiry about: 3D-NC10429 8-(4-Chlorophenylthio)adenosine 3',5'-cyclic monophosphate monosodium salt
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