4-Chloro-5-aminopyrimidine
CAS: 54660-78-5
Ref. 3D-NC57423
| 1g | To inquire | |
| 2g | To inquire | |
| 5g | To inquire | |
| 10g | To inquire | |
| 500mg | To inquire |
Product Information
- 4-Chloropyrimidin-5-amine
- 4-Chloropyrimidin-5-Amine
- 5-Pyrimidinamine, 4-Chloro-
- 4-Chloropyrimidin-5-Aminato
4-Chloro-5-aminopyrimidine (4CAP) is an inhibitor of the enzyme purine nucleoside phosphorylase, which is involved in the synthesis of purines and pyrimidines. 4CAP has potent inhibitory activity with a Ki value of 0.06 μM, which is comparable to that of zebularine. 4CAP has also been shown to have antiinflammatory properties in lung tissue. The molecular modeling studies show that 4CAP binds to the hydroxyl group on the enzyme and prevents it from forming a covalent bond with its substrate. This causes a decrease in the rate of reaction time for the enzyme, resulting in decreased production of purines and pyrimidines.
Chemical properties
Technical inquiry about: 3D-NC57423 4-Chloro-5-aminopyrimidine
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