Cyclic di-adenosine monophosphate sodium salt
CAS: 54447-84-6
Ref. 3D-NC64061
| 1mg | To inquire | ||
| 2mg | To inquire | ||
| 5mg | To inquire | ||
| 10mg | To inquire | ||
| 20mg | To inquire |
Product Information
- Cyclic diadenylateCyclic di-AMPc-di-AMP3',5'-Cyclic diadenylic acid
Cyclic di-adenosine monophosphate sodium salt (c-di-AMP) is a cyclic nucleotide that is structurally similar to its natural counterpart, Adenosine 5'-triphosphate. It binds to the Toll-like receptor 4 (TLR4) and blocks the activation of TLR4 by lipopolysaccharide, thereby inhibiting the downstream inflammatory response. c-di-AMP also inhibits the production of proinflammatory cytokines such as TNFα, IL1β, and IL6 in vitro. c-di-AMP has shown anti-inflammatory properties in vivo and can be used for the treatment of infectious diseases.
Chemical properties
Technical inquiry about: 3D-NC64061 Cyclic di-adenosine monophosphate sodium salt
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