7-Deaza-2'-deoxyguanosine
CAS: 86392-75-8
Ref. 3D-ND02887
| 25mg | 99.00 € | ||
| 50mg | 161.00 € | ||
| 100mg | 252.00 € | ||
| 250mg | 497.00 € | ||
| 500mg | 712.00 € |
Product Information
- 7-Deaza-2'-deoxy-D-guanosine
- 2-Amino-7-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
- 4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-7-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-1,7-dihydro-
7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.
Chemical properties
Technical inquiry about: 3D-ND02887 7-Deaza-2'-deoxyguanosine
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