1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino-1,3-dihydro-2-oxo-1,3,5-triazine

Ref. 3D-ND04706

Product Information

• Name: 1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino-1,3-dihydro-2-oxo-1,3,5-triazine

Description

1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino-1,3-dihydro-2-oxo-1,3,5-triazine is a nucleoside that is used as an anticancer drug. It is a modified nucleotide with a 2'-deoxyribofuranosyl group attached to the 3' carbon of the sugar moiety. It has been shown to be active against viruses and cancer cells. 1-(2'-Deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-4-amino -1,3 -dihydro -2 -oxo -1,3,5 -triazine inhibits the replication of DNA by inhibiting DNA polymerase. This in turn prevents RNA synthesis and protein synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 464.48 g/mol
• Formula: C₂₄H₂₄N₄O₆
• Purity: Min. 95%
• InChI: InChI=1S/C24H24N4O6/c1-14-3-7-16(8-4-14)21(29)32-12-19-18(34-22(30)17-9-5-15(2)6-10-17)11-20(33-19)28-13-26-23(25)27-24(28)31/h3-10,13,18-20H,11-12H2,1-2H3,(H2,25,27,31)/t18-,19-,20?/m1/s1
• InChI key: InChIKey=XFWRGHFUGJXDEX-LEAGNCFPSA-N
• SMILES: Cc1ccc(C(=O)OC[C@H]2OC(n3cnc(N)nc3=O)C[C@H]2OC(=O)c2ccc(C)cc2)cc1