2'-Deoxy-L-guanosine

CAS: 22837-44-1

Ref. 3D-ND05774

Product Information

• Name: 2'-Deoxy-L-guanosine
• Synonyms: 9-(2-Deoxy-β-L-erythro-pentofuranosyl)guanine

Description

2'-Deoxy-L-guanosine is a nucleoside that is used as an antibiotic. It inhibits protein synthesis, which leads to cell death. This drug has a high level of resistance against bacteria and is effective in the treatment of gram-positive bacteria. 2'-Deoxy-L-guanosine binds to the ribose phosphate backbone of DNA, phosphorylating it and preventing the base pairing of adenosine with thymine. This inhibits the production of DNA and RNA, leading to cell death. 2'-Deoxy-L-guanosine has been shown to be active against Listeria monocytogenes and Mycobacterium tuberculosis. The enantiomer form is more potent than the racemic mixture, but both forms are effective antibiotics.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.25 g/mol
• Formula: C₁₀H₁₃N₅O₄
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H13N5O4/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6/h3-6,16-17H,1-2H2,(H3,11,13,14,18)/t4-,5+,6-/m1/s1
• InChI key: InChIKey=YKBGVTZYEHREMT-NGJCXOISSA-N
• SMILES: Nc1nc2c(ncn2[C@H]2C[C@@H](O)[C@H](CO)O2)c(=O)[nH]1