9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine
Ref. 3D-ND09527
| 25mg | 197.00 € | ||
| 50mg | 325.00 € | ||
| 100mg | 485.00 € | ||
| 250mg | 979.00 € | ||
| 500mg | 1,286.00 € |
Product Information
- 2'-Deoxy-2'-fluoroisoguanosine
9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine is an oligonucleotide with a fluorinated nucleobase that is used to stabilize DNA duplexes. It is synthesized from 5'-deoxy-5'-fluorocytidine, which is a phosphoramidite, and 2',3',5'-triacetylpyrimidine, which is a substituent. The deprotection of the fluorinated oligonucleotide can be achieved by treatment with sodium hydroxide in ethanol or hydrochloric acid in acetic acid. 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine has been shown to be stable and antiparallel when incorporated into double stranded DNA molecules.
Chemical properties
Technical inquiry about: 3D-ND09527 9-(2'-Deoxy-2'-fluoro-b-D-ribofuranosyl)-isoguanine
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