2'-Deoxy-5-methylcytidine-5'-monophosphate disodium

CAS: 2498-41-1

Ref. 3D-ND10012

Product Information

• Name: 2'-Deoxy-5-methylcytidine-5'-monophosphate disodium
• Synonyms: 5-MedCMP disodium, 2'-Deoxy-5-Methylcytidine 5'-(Dihydrogen Phosphate), 2'-Deoxy-5-methylcytidine 5'-monophosphate, 2′-Deoxy-5-methyl-5′-cytidylic acid, 2′-Deoxy-5-methylcytidine 5′-phosphate, 5-Methyl dCMP, 5-Methyl-deoxycytidylic acid, 5-Methyldeoxycytidine monophosphate, 5-Methyldeoxycytidylic acid, 5′-Cytidylic acid, 2′-deoxy-5-methyl-, Cytidine, 2′-deoxy-5-methyl-, 5′-(dihydrogen phosphate), Cytidine, 2′-deoxy-5-methyl-, 5′-phosphate, Deoxy-5-methylcytidylic acid

Description

2'-Deoxy-5-methylcytidine-5'-monophosphate disodium (2D5MCP) is a nucleoside analog that inhibits the synthesis of DNA. It is used in the treatment of cervical cancer and other cancers that are dependent on DNA synthesis. 2D5MCP works by binding to and inhibiting the activity of an enzyme called DNA polymerase, which is needed for DNA replication. This drug also has been shown to inhibit fatty acid synthase enzymes and surface glycoprotein enzymes, which may be responsible for its anti-cancer effects. 2D5MCP has been shown to have an effective dose range between 50 and 150 mg/kg, with no significant side effects seen at doses up to 300 mg/kg. 2D5MCP does not bind to plasma proteins or erythrocytes, so it can be administered intravenously without risk of tissue damage caused by osmotic lysis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 365.19 g/mol
• Formula: C₁₀H₁₄N₃O₇PNa₂
• Purity: Min. 95%
• Color/Form: White Powder