1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil
Ref. 3D-ND137579
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Product Information
1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil is an anticancer and antiviral nucleoside. It has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1). This compound inhibits viral DNA synthesis by competing with the natural substrate for HIV reverse transcriptase, 3'-deoxyadenosine 5'-triphosphate. It also prevents the in vitro proliferation of lymphocytes, which may be due to its inhibition of DNA synthesis. 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil is also an activator of phosphoramidites, which are used in the production of oligonucleotides and other modified nucleosides.
Chemical properties
Technical inquiry about: 3D-ND137579 1-(3'-Deoxy-3'-fluoro-b-D-xylofuranosyl)-5-methyluracil
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