5′-O-DMT-LNA N-dmf guanosine
CAS: 709641-78-1
Ref. 3D-ND182843
1g | To inquire | ||
50mg | To inquire | ||
100mg | To inquire | ||
250mg | To inquire | ||
500mg | To inquire |
Product Information
- N′-[9-[2,5-Anhydro-4-C-[[bis(4-methoxyphenyl)phenylmethoxy]methyl]-α-L-lyxofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-N,N-dimethylm ethanimidamide
5′-O-DMT-LNA N-dmf guanosine is a modified nucleoside that has anticancer, antiviral, and anti-inflammatory activities. It binds to the ribonucleotide reductase enzyme, which is an enzyme required for the production of new DNA and RNA. This binding prevents the synthesis of new DNA and RNA in cells, leading to cell death. 5′-O-DMT-LNA N-dmf guanosine has been shown to be active against cancer cells in vitro and in vivo. In addition, it also inhibits replication of human immunodeficiency virus type 1 (HIV) by binding to reverse transcriptase (RT), which is an enzyme critical for HIV replication.
Chemical properties
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