2,6-Dichloro-7-methylpurine

CAS: 2273-93-0

Ref. 3D-ND29030

Product Information

• Name: 2,6-Dichloro-7-methylpurine
• Synonyms: 2,6-Dichloro-7-methyl-7H-purine, 5,7-Dichloro-1-methyl-1H-imidazo[4,5-d]pyrimidine, 7H-Purine, 2,6-dichloro-7-methyl-, NSC 7853, Purine, 2,6-dichloro-7-methyl-

Description

2,6-Dichloro-7-methylpurine (2,6-DCMP) is a chlorinated purine analog that has anticancer activity. It is an ATP competitive inhibitor that inhibits protein synthesis by competitively binding to the alpha subunit of the ribosome. 2,6-DCMP has been shown to have strong antiviral activity against human immunodeficiency virus and cytotoxic effects on human adenocarcinoma cells in vitro. The IC50 values for this compound are 50 nM against HIV and 5 μM against human adenocarcinoma cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 203.03 g/mol
• Formula: C₆H₄Cl₂N₄
• Purity: Min. 95%
• InChI: InChI=1S/C6H4Cl2N4/c1-12-2-9-5-3(12)4(7)10-6(8)11-5/h2H,1H3
• InChI key: InChIKey=HVMUWHZAZGTMJK-UHFFFAOYSA-N
• SMILES: Cn1cnc2nc(Cl)nc(Cl)c21