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2,6-Dichloro-7-methylpurine
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2,6-Dichloro-7-methylpurine

CAS: 2273-93-0

Ref. 3D-ND29030

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Estimated delivery in United States, on Friday 28 Jun 2024

Product Information

Name:
2,6-Dichloro-7-methylpurine
Synonyms:
  • 2,6-Dichloro-7-methyl-7H-purine
  • 5,7-Dichloro-1-methyl-1H-imidazo[4,5-d]pyrimidine
  • 7H-Purine, 2,6-dichloro-7-methyl-
  • NSC 7853
  • Purine, 2,6-dichloro-7-methyl-
Description:

2,6-Dichloro-7-methylpurine (2,6-DCMP) is a chlorinated purine analog that has anticancer activity. It is an ATP competitive inhibitor that inhibits protein synthesis by competitively binding to the alpha subunit of the ribosome. 2,6-DCMP has been shown to have strong antiviral activity against human immunodeficiency virus and cytotoxic effects on human adenocarcinoma cells in vitro. The IC50 values for this compound are 50 nM against HIV and 5 μM against human adenocarcinoma cells.

Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
203.03 g/mol
Formula:
C6H4Cl2N4
Purity:
Min. 95%
InChI:
InChI=1S/C6H4Cl2N4/c1-12-2-9-5-3(12)4(7)10-6(8)11-5/h2H,1H3
InChI key:
InChIKey=HVMUWHZAZGTMJK-UHFFFAOYSA-N
SMILES:
Cn1cnc2nc(Cl)nc(Cl)c21
MDL:
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EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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