2'-Deoxy-5-ethynyluridine
CAS: 61135-33-9
Ref. 3D-NE08701
| 1g | 430.00 € | ||
| 2g | 693.00 € | ||
| 5g | 1,393.00 € | ||
| 250mg | 163.00 € | ||
| 500mg | 265.00 € |
Product Information
- 2'-Deoxy-5-ethynyluridine5-Ethynyl-2'-deoxyuridine5-EdU
- 2,4(1H,3H)-pyrimidinedione, 1-(2-deoxypentofuranosyl)-5-ethynyl-
- 5-Ethynyl-2'-Deoxyuridine
- Uridine, 2'-Deoxy-5-Ethynyl-
2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.
Chemical properties
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