Product Information
- Ym 90709
- 2,3-Dimethoxy-6,6-Dimethyl-5,6-Dihydrobenzo[7,8]Indolizino[2,3-B]Quinoxaline
YM 90709 is a monoclonal antibody that binds to the receptor for the cytokine GM-CSF and blocks the binding of this cytokine, thereby inhibiting eosinophil function. YM 90709 has been shown to inhibit colony-stimulating factor (CSF) production, which is required for neutrophil and monocyte transformation and for lymphocyte activation. This agent also inhibits eosinophilic responses in functional assays by blocking IL-5 and IL-3 binding to their receptors on eosinophils. YM 90709 has been shown to be effective in advanced clinical trials.
Chemical properties
Technical inquiry about: 3D-NGA76988 YM 90709
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