2',3'-O-Isopropylideneuridine

CAS: 362-43-6

Ref. 3D-NI05371

Product Information

• Name: 2',3'-O-Isopropylideneuridine
• Synonyms: Isopropylideneuridine2',3'-O-Isopropylidene-D-uridine, 1-[2,3-O-(1-methylethylidene)pentofuranosyl]pyrimidine-2,4(1H,3H)-dione, 2',3'-O-(1-methylethylidene)uridine, 2,3-Isopropylideneuridine, 2,3-O-Isopropylideneuridine, 2′,3′-O-(1-Methylethylidene)uridine, Furo[3,4-d]-1,3-dioxole, uridine deriv., NSC 520038, Uridine 2′,3′-acetonide, Uridine, 2′,3′-O-(1-methylethylidene)-, Uridine, 2′,3′-O-isopropylidene-

Description

2',3'-O-Isopropylideneuridine is an inhibitor of the pestivirus, which is a member of the family Poxviridae and causes disease in humans. It has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-O-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture. 2',3'-O-Isopropylideneuridine binds to the viral RNA polymerase and inhibits its activity, preventing viral replication. The drug has been shown to be active against HIV-1 and HIV-2 isolates, as well as against a variety of other viruses that infect humans, such as Hepatitis C virus and herpes simplex virus type 1.

• Brand: Biosynth

Chemical properties

• Molecular weight: 284.27 g/mol
• Formula: C₁₂H₁₆N₂O₆
• Purity: Min. 95%
• Color/Form: White Powder