2',3'-O-Isopropylideneuridine
CAS: 362-43-6
Ref. 3D-NI05371
10g | 140.00 € | ||
25g | 183.00 € | ||
50g | 279.00 € | ||
100g | 463.00 € | ||
250g | 780.00 € |
Product Information
- Isopropylideneuridine2',3'-O-Isopropylidene-D-uridine
- 1-[2,3-O-(1-methylethylidene)pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
- 2',3'-O-(1-methylethylidene)uridine
- 2,3-Isopropylideneuridine
- 2,3-O-Isopropylideneuridine
- 2′,3′-O-(1-Methylethylidene)uridine
- Furo[3,4-d]-1,3-dioxole, uridine deriv.
- NSC 520038
- Uridine 2′,3′-acetonide
- Uridine, 2′,3′-O-(1-methylethylidene)-
- See more synonyms
- Uridine, 2′,3′-O-isopropylidene-
2',3'-O-Isopropylideneuridine is an inhibitor of the pestivirus, which is a member of the family Poxviridae and causes disease in humans. It has been shown to inhibit binding of pestivirus inhibitors by monoclonal antibodies. 2',3'-O-Isopropylideneuridine was also found to inhibit the replication of human immunodeficiency virus (HIV) in tissue culture. 2',3'-O-Isopropylideneuridine binds to the viral RNA polymerase and inhibits its activity, preventing viral replication. The drug has been shown to be active against HIV-1 and HIV-2 isolates, as well as against a variety of other viruses that infect humans, such as Hepatitis C virus and herpes simplex virus type 1.
Chemical properties
Technical inquiry about: 3D-NI05371 2',3'-O-Isopropylideneuridine
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