6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine

CAS: 2239-64-7

Ref. 3D-NM02964

Product Information

• Name: 6-Mercapto-9-(2'-deoxy-β-D-ribofuranosyl)purine
• Synonyms: 2'-Deoxy-6-thioinosine6-Thiopurine-2'-deoxyriboside6-Mercaptopurine-2'-deoxyriboside, 2'-Deoxy-6-thioinosine, 6-Mercaptopurine deoxyribonucleoside, 6-Mercaptopurine deoxyriboside, 6-Mercaptopurine-2'-deoxyribonucleoside, 9-(2-Deoxy-beta-D-erythro-pentofuranosyl)-9H-purine-6(1H)-thiol, 9-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-9H-purine-6-thiol, 9-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-9H-purine-6-thione, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,9-dihydro-6H-purine-6-thione, 9-(2-deoxypentofuranosyl)-3,9-dihydro-6H-purine-6-thione, 9H-Purine-6(1H)-thione, 9-(2-deoxy-beta-D-erythro-pentofuranosyl)-, 9H-Purine-6(1H)-thione, 9-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-, Inosine, 2'-deoxy-6-thio- (9CI), Inosine, 2′-deoxy-6-thio-, Nsc 409366, Nsc 90557

Description

6-Mercapto-9-(2'-deoxy-b-D-ribofuranosyl)purine (6MPD) is a purine nucleoside that is used in the preparation of glycosidic bonds. It forms a glycosidic bond with the terminal residue of an oligosaccharide, which leads to the formation of an oligodeoxynucleotide. 6MPD also has binding properties to DNA binding proteins, and it can be used as a growth factor. 6MPD is obtained by reacting 3-chloroperoxybenzoic acid with sodium trifluoroacetate in the presence of mercaptoethanol and sodium hydroxide. This reaction yields 6MPD as a white solid with a melting point of 179°C.

• Brand: Biosynth

Chemical properties

• Molecular weight: 268.29 g/mol
• Formula: C₁₀H₁₂N₄O₃S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C10H12N4O3S/c15-2-6-5(16)1-7(17-6)14-4-13-8-9(14)11-3-12-10(8)18/h3-7,15-16H,1-2H2,(H,11,12,18)
• InChI key: InChIKey=WACLJMMBCDNRJE-UHFFFAOYSA-N
• SMILES: OCC1OC(n2cnc3c(=S)nc[nH]c32)CC1O