6-Thio-9-(β-D-arabinofuranosyl)purine

CAS: 892-49-9

Ref. 3D-NM06321

Product Information

• Name: 6-Thio-9-(β-D-arabinofuranosyl)purine
• Synonyms: 6-Mercaptopurine arabinoside, 6-Mercapto-9-(β-<span class="text-smallcaps">D</span>-arabinofuranosyl)purine, 6-Thio-9-beta-D-arabinofuranosylpurine, 6-Thio-9-β-<span class="text-smallcaps">D</span>-arabinofuranosylpurine, 6H-Purine-6-thione, 9-beta-D-arabinofuranosyl-1,9-dihydro- (9CI), 6H-Purine-6-thione, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-1,9-dihydro-, 6MP-Arabinoside, 9-(β-<span class="text-smallcaps">D</span>-Arabinofuranosyl)-6-mercaptopurine, 9-beta-D-Arabinofuranosyl-1,9-dihydro-6H-purine-6-thione, 9-beta-D-Arabinofuranosyl-9H-purine-6-thiol, 9-beta-D-arabinofuranosyl-3,9-dihydro-6H-purine-6-thione, 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-1,9-dihydro-6H-purine-6-thione, 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-9H-purine-6-thiol, 9-β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-9H-purine-6-thione, 9H-Purine-6-thiol, 9-β-<span class="text-smallcaps">D</span>-arabinofuranosyl-, 9H-purine-6-thiol, 9-beta-D-arabinofuranosyl-, 9beta-Arabinofuranosyl-9-H-purine-6-thiol, D-, Ara-6Mp, Ara-MP, Arabinofuranosyl-6-mercaptopurine, Arabinosyl-6-mercaptopurine, Brn 5297846, Nsc 406021, beta-Ara-6-MP, beta-D-Arabinofuranosyl-6-mercaptopurine, beta-D-Arabinosyl-6-mercaptopurine, β-<span class="text-smallcaps">D</span>-Arabinofuranosyl-6-mercaptopurine, β-<span class="text-smallcaps">D</span>-Arabinosyl-6-mercaptopurine

Description

6-Thio-9-(b-D-arabinofuranosyl)purine is a purine analog that inhibits the enzyme uridine phosphorylase, which is involved in the metabolism of uridine. It has been shown to inhibit the growth of L1210 cells and also to be effective against subcutaneous tumors in mice. 6-Thio-9-(b-D-arabinofuranosyl)purine is active against schistosomiasis in mice, with an LD50 of 1 mg/kg. This drug has also been shown to have potential antitumor activity and was able to inhibit the growth of human lymphocytes and leukocytes.

• Brand: Biosynth

Chemical properties

• Molecular weight: 284.29 g/mol
• Formula: C₁₀H₁₂N₄O₄S
• Purity: Min. 95%
• Color/Form: Powder