S-(4-Nitrobenzyl)-6-thioinosine

CAS: 38048-32-7

Ref. 3D-NN09410

Product Information

• Name: S-(4-Nitrobenzyl)-6-thioinosine
• Synonyms: 6-[(4-Nitrobenzyl)thio]-9-b-D-ribofuranosylpurineNBMPR
• Brand: Biosynth
• Description: S-(4-Nitrobenzyl)-6-thioinosine (SBT) is a nucleoside with biochemical properties that are similar to those of adenosine. SBT is an equilibrative nucleoside, which means that it can bind to both DNA and RNA. It has been shown to be effective in inhibiting the growth of cancer cells in vitro by binding to DNA. SBT binds to the purine nucleotide transporter and prevents the uptake of uridine, adenosine, and other nucleosides into the cell. This process leads to a decrease in intracellular concentrations of these nucleosides. SBT also binds to divalent metal ions such as copper or zinc, which may affect its activity on cancer cells.

Chemical properties

• Molecular weight: 419.41 g/mol
• Formula: C₁₇H₁₇N₅O₆S
• Purity: Min. 98 Area-%
• Color/Form: White Off-White Powder