Nicotinamide 1,N6-ethenoadenine dinucleotide

CAS: 38806-38-1

Ref. 3D-NN26196

Product Information

• Name: Nicotinamide 1,N6-ethenoadenine dinucleotide
• Synonyms: 1,N6-Ethenonicotinamide adenine dinucleotide1,N6-Etheno NAD, Nicotinamide 1,N(6)-ethenoadenine dinucleotide, 1,N(6)-Etheno-NAD, Epsilon NAD, Pyridinium, 3-(aminocarbonyl)-1-(5-O-(hydroxy(phosphonooxy)phosphinyl)-beta-D-ribofuranosyl)-, hydroxide, inner salt, 5'-5'-ester with 3-beta-D-ribofuranosyl-3H-imidazo(2,1-i)purine, [(2R,3S,4R,5R)-5-(3-carbamoylpyridin-1-ium-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methyl [[(2R,3S,4R,5R)-3,4-dihydroxy-5-imidazo[2,1-f]purin-3-yl-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl] phosphate
• CAS: 38806-38-1

Description

Nicotinamide 1,N6-ethenoadenine dinucleotide (NADH) is an enzyme form that binds to the active site of glutamate dehydrogenase (GDH). This binding prevents GDH from catalyzing the oxidation of NADH to NAD+, which is necessary for GDH activity. Nicotinamide 1,N6-ethenoadenine dinucleotide is a noncompetitive inhibitor that binds with a higher affinity than the substrate. It has been shown to be effective in inhibiting GDH in a model system and in enzyme preparations. The binding constant for nicotinamide 1,N6-ethenoadenine dinucleotide is 2 mM. The optimum pH for nicotinamide 1,N6-ethenoadenine dinucleotide activity is 6.8.

• Brand: Biosynth

Chemical properties

• Molecular weight: 687.45 g/mol
• Formula: C₂₃H₂₇N₇O₁₄P₂
• Purity: Min. 97 Area-%
• Color/Form: White Off-White Powder