Product Information
- 1-(5-O-Phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
- 1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-phosphono-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
- 1H-1,2,4-triazole-3-carboxamide, 1-(5-O-phosphono-beta-D-ribofuranosyl)-
- NSC 274937
- Ribavirin 5′-monophosphate
- Ribavirin 5′-phosphate
- Ribavirin monophosphate
- Virazole 5′-phosphate
- 1H-1,2,4-Triazole-3-carboxamide, 1-(5-O-phosphono-β-D-ribofuranosyl)-
- 1-(5-O-Phosphono-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide
- See more synonyms
Ribavirin is an antiviral drug that is used in the treatment of a number of viral infections, including chronic hepatitis C, respiratory syncytial virus, and influenza. Ribavirin inhibits the synthesis of RNA by interfering with ribonucleotide reductase. Ribavirin 5'-monophosphate sodium salt (RPMPS) is a prodrug that is hydrolyzed to form ribavirin 5'-triphosphate (RTP). This active form inhibits the polymerase chain reaction by binding to DNA polymerase. Ribavirin has been shown to be effective against cell lines resistant to other antiviral drugs such as zirconium oxide. RPMPS has also been shown to be an inhibitor of structural analysis and energy metabolism in erythrocytes.
Chemical properties
Technical inquiry about: 3D-NR46024 Ribavirin 5'-monophosphate sodium salt
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