9-(2',3',5'-Tri-O-acetyl-β-D-ribofuranosyl)-6-chloropurine

CAS: 5987-73-5

Ref. 3D-NT10156

Product Information

• Name: 9-(2',3',5'-Tri-O-acetyl-β-D-ribofuranosyl)-6-chloropurine
• Synonyms: 2',3',5'-Tri-O-acetyl-6-chloroinosine2',3',5'-Tri-O-acetyl- 6-Chloro-9-(β-D-ribofuranosyl)purine

Description

9-(2',3',5'-Tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine is an anticancer drug that belongs to the class of nucleosides. It is a modified nucleoside with a 2'-deoxyribose sugar and a 6-chloropurine base. The synthesis of 9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)-6-chloropurine can be achieved by phosphoramidite chemistry. Modified nucleosides have been found to have high antiviral and antitumour activities, as well as being promising for the treatment of HIV infections. 9-(2',3',5'-tri-O acetyl b D ribofuranosyl)-6 chloropurine has also been shown to inhibit the replication of RNA in cells infected with HIV, although it has not yet been used in humans.

• Brand: Biosynth

Chemical properties

• Molecular weight: 412.78 g/mol
• Formula: C₁₆H₁₇ClN₄O₇
• Purity: Min. 95%
• Color/Form: Yellow Powder
• InChI: InChI=1S/C16H17ClN4O7/c1-7(22)25-4-10-12(26-8(2)23)13(27-9(3)24)16(28-10)21-6-20-11-14(17)18-5-19-15(11)21/h5-6,10,12-13,16H,4H2,1-3H3/t10-,12-,13-,16?/m1/s1
• InChI key: InChIKey=INOTYVPMBNDAFK-AARXTDBFSA-N
• SMILES: CC(=O)OC[C@H]1OC(n2cnc3c(Cl)ncnc32)[C@H](OC(C)=O)[C@@H]1OC(C)=O