Diosmetin-7-neohesperidoside

CAS: 38665-01-9

Ref. 3D-OD137876

Product Information

• Name: Diosmetin-7-neohesperidoside
• Synonyms: Neodiosmin4',5-Dihydroxylflavanone-7-O-a-L-rhamnosyl (1?2)-b-D-glucopyranoside, 4H-1-Benzopyran-4-one, 7-[[2-O-(6-deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-, 4′,5-Dihydroxylflavanone-7-O-α-<span class="text-smallcaps">L</smallcap>-rhamnosyl (1→2)-β-<smallcap>D</span>-glucopyranoside, 7-[[2-O-(6-Deoxy-α-<span class="text-smallcaps">L</smallcap>-mannopyranosyl)-β-<smallcap>D</span>-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, Neodiosmin
• CAS: 38665-01-9

Description

Diosmetin-7-neohesperidoside is a bioactive phenolic compound that is extracted from the Chinese herb Dioscorea opposita. It has been found to have potential as a drug target for the treatment of hypertension and dyslipidemia. The chemical structure of diosmetin-7-neohesperidoside consists of a hydroxyl group, hydrogen bond, and phenolic acid. Diosmetin-7-neohesperidoside has been shown to bind with gamma-aminobutyric acid (GABA) receptors in animal studies, which may be due to its structural similarity with ferulic acid. This binding inhibits chloride ion influx into cells and subsequent activation of chloride channels, leading to an increased intracellular chloride concentration, resulting in reduced neuronal excitability.

• Brand: Biosynth

Chemical properties

• Molecular weight: 608.54 g/mol
• Formula: C₂₈H₃₂O₁₅
• Purity: Min. 95%
• InChI: InChI=1S/C28H32O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/h3-8,10,19,21-31,33-37H,9H2,1-2H3/t10-,19+,21-,22+,23+,24-,25+,26+,27-,28+/m0/s1
• InChI key: InChIKey=VCCNKWWXYVWTLT-CYZBKYQRSA-N
• SMILES: COc1ccc(-c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O[C@@H]4O[C@@H](C)[C@H](O)[C@@H](O)[C@H]4O)cc3o2)cc1O