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GM3-Ganglioside sodium
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GM3-Ganglioside sodium

CAS: 54827-14-4

Ref. 3D-OG16188

1mg
578.00 €
2mg
1,033.00 €
5mg
2,228.00 €
10mg
4,213.00 €
Estimated delivery in United States, on Wednesday 18 Dec 2024

Product Information

Name:
GM3-Ganglioside sodium
Synonyms:
  • aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer
  • G<sub>Lac1</sub>
  • G<sub>M3</sub>
  • GLac1
  • GM3
  • Ganglioside G<sub>M3</sub>
  • Ganglioside M3
  • Ganglioside M<sub>3</sub>
  • Gangliosides, GM3
  • Hematoside
  • See more synonyms
  • Monosialodihexosylganglioside
  • Sialosyllactosylceramide
  • Ganglioside GM3
Description:

Ganglioside GM3 (sodium salt) has a core disaccharide structure (Galβ1,4Glc) with sialic acid linked α2,3 to the galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). Ganglioside GM3 is strongly associated with human tumors, such as: lung, brain and melanomas, where it is over expressed. It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019). GM3 ganglioside is implicated in various other diseases involving chronic inflammation, such as: insulin resistance, leptin resistance, T-cell function and immune disorders (e.g., allergic asthma). It has also been shown to play an essential role in murine and human auditory systems, and a common pathological feature of GM3S deficiency is deafness (Inokuchi, 2018).

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
1,252 g/mol
Formula:
C64H118N2O21·xNa
Purity:
Min. 98 Area-%
Color/Form:
White Powder
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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