GM2-Oligosaccharide-sp-biotin
Ref. 3D-OO57595
| 1mg | 6,115.00 € | ||
| 100µg | 813.00 € | ||
| 500µg | 3,516.00 € |
Product Information
Biotin-labelled oligosaccharide domain of the monosialylated glycosphingolipid GM2 of a-series. The compound is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system. GM2 is also overexpressed in melanomas and other tumours of neuro-ecto origin. Moreover, the sugar moiety of this ganglioside is a receptor allowing viral infection of cells with reovirus and rotavirus.
Chemical properties
Technical inquiry about: 3D-OO57595 GM2-Oligosaccharide-sp-biotin
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