Tin protoporphyrin IX dichloride

CAS: 14325-05-4

Ref. 3D-PAA32505

Product Information

• Name: Tin protoporphyrin IX dichloride
• Synonyms: 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, tin complex, NSC 267099, Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N²¹,N²²,N²³,N²⁴]-, dihydrogen, (OC-6-13)-, Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, dihydrogen, (OC-6-13)-, Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN²¹,κN²²,κN²³,κN²⁴]-, hydrogen (1:2), (OC-6-13)-, Tin protoporphyrin, Tin(4+) 2,18-Bis(2-Carboxyethyl)-7,12-Diethenyl-3,8,13,17-Tetramethylporphine-21,22,23,24-Tetraide, Tin, [dihydrogen protoporphyrin IX-ato(2-)]-, Tinprotoporphyrin, tin protoporphyrin IX, Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-N21,N22,N23,N24]-, dihydrogen, (OC-6-13)-, Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, hydrogen (1:2), (OC-6-13)-, Stannate(2-), dichloro[7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoato(4-)-κN21,κN22,κN23,κN24]-, dihydrogen, (OC-6-13)-

Description

Tin protoporphyrin IX dichloride (SnPPIX) is a mitochondrial membrane potential stabilizer that has been shown to restore the function of ATP-sensitive potassium channels in cells. It also inhibits protease activity and cell signaling pathways, which may be due to its ability to bind to the active site of enzymes involved in these processes. Tin protoporphyrin IX dichloride has been shown to have significant cytotoxicity against HL60 cells, with an IC50 of 0.3 µM. SnPPIX also has fluorescence properties, which can be used as a probe for measuring intracellular levels of ATP.

• Brand: Biosynth

Chemical properties

• Molecular weight: 750.25 g/mol
• Formula: C₃₄H₃₂Cl₂N₄O₄Sn
• Purity: Min. 95%