Product Information
- 2-Furancarboxylic Acid, 3-Bromo-
- 3-Bromofuran-2-Carboxylic Acid
3-Bromo-2-furoic acid is an intermediate in the synthesis of 3,4-dihydro-2H-pyran. It is produced by the oxidation of 2-furoic acid and can be synthesized by the reaction of furyl with biphenyl. 3-Bromo-2-furoic acid is a competitive inhibitor of glutamate dehydrogenase and glutamate synthetase. Inhibition of these enzymes prevents the conversion of glutamate to glutamine, which leads to elevated levels of glutamate in the brain, resulting in neurotoxicity. 3-Bromo-2-furoic acid also inhibits nicotinic acetylcholine receptors at low concentrations and has been shown to inhibit mitochondrial respiration. This drug has been used to treat hypertension in rats.
Chemical properties
Technical inquiry about: 3D-PAA90390 3-Bromo-2-furoic Acid
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