N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite

CAS: 171486-59-2

Ref. 3D-PB139174

Product Information

• Name: N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite
• Synonyms: N- Benzoyl- 5'- O- [bis(4- methoxyphenyl) phenylmethyl] - 2'- O- 2- propyn- 1- yl- adenosine 3'- [2- cyanoethyl N, N- bis(1- methyle thyl) phosphoramidite]
• Brand: Biosynth
• Description: N6-Benzoyl-5'-O-DMT-2'-O-propynyladenosine 3'-CE phosphoramidite is a modified nucleoside, which is an important building block for DNA and RNA synthesis. It is synthesized by the condensation of 6-benzoyladenosine with 2'-O-propynyladenosin. The stability of this compound has been demonstrated by its resistance to hydrolysis and oxidation, while it can also be activated with a variety of activators, including NaBH4 or NaCNBH3. This novel nucleotide has shown anticancer activity in vivo and antiviral activity against HIV.

Chemical properties

• Molecular weight: 911.98 g/mol
• Formula: C₅₀H₅₄N₇O₈P
• Purity: Min. 95%