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(1R,4R,9R,10R)-2,8,16-Trihydroxy-5,5,9-trimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexade…
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(1R,4R,9R,10R)-2,8,16-Trihydroxy-5,5,9-trimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one

CAS: 39388-57-3

Ref. 3D-PBA38857

5mg
702.00 €
10mg
1,008.00 €
25mg
1,889.00 €
50mg
3,022.00 €
Estimated delivery in United States, on Tuesday 18 Feb 2025

Product Information

Name:
(1R,4R,9R,10R)-2,8,16-Trihydroxy-5,5,9-trimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one
Synonyms:
  • Kamebanin
Description:

(1R,4R,9R,10R)-2,8,16-Trihydroxy-5,5,9-trimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one is a natural product that is found in the roots of the plant Isodon rugulosus and has been shown to have anti-inflammatory activities in vitro. This compound binds to the p38 mitogen activated protein kinase (MAPK) pathway and inhibits its activation by reducing phosphorylation of the p38 MAPK molecule. It also inhibits the production of proinflammatory cytokines by inhibiting nuclear factor kappa B (NFκB) translocation. The mechanism of action of this compound may be due to its ability to inhibit NFκB translocation and subsequent transcriptional activity or its ability to inhibit IL-1β production by blocking NFκB signaling pathways.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
334.4 g/mol
Formula:
C20H30O4
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
Flash point:
Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

Technical inquiry about: 3D-PBA38857 (1R,4R,9R,10R)-2,8,16-Trihydroxy-5,5,9-trimethyl-14-methylidenetetracyclo[11.2.1.01,10.04,9]hexadecan-15-one

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