Bradykinin (Human, Bovine, Rat, Mouse)
Ref. 3D-PBK-4002
| 25mg | 348.00 € | ||
| 100mg | 722.00 € |
Product Information
- Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg • 2AcOH • 3H2O
Bradykinin is a peptide that is generated by the breakdown of kininogen, a protein found in the blood. Bradykinin is an important mediator of inflammation and vasodilation. It also has many other functions, such as the regulation of tissue fluid homeostasis, pain perception, and the release of hormones from endocrine glands. The human form of bradykinin is derived from the precursor molecule kininogen through proteolytic cleavage by kallikrein or kallidin and subsequent conversion to bradykinin by either carboxypeptidases A or B. The bovine form arises from proteolysis at Arg-Arg-Lys-Arg sites whereas rat bradykinin arises from Arg-Lys sites in kininogen. Mouse bradykinin arises primarily from Arg-Arg sites in kininogen.
Chemical properties
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