Product Information
- 2-Benzamido-5-nitrothiazole
- Benzamide, N-(5-nitro-2-thiazolyl)-
- Benzamido-2-nitro-5-thiazole
- Brn 0023059
- N-(5-Nitrothiazol-2-yl)benzamide
- N-(5-nitro-1,3-thiazol-2-yl)benzamide
- Nsc 87574
- Thiazole, 2-benzamido-5-nitro-
N-(5-Nitro-thiazol-2-yl)-benzamide is a noncompetitive inhibitor of the enzyme succinate dehydrogenase and is used as an molluscicide. It binds to the active site of the enzyme, which is located in the mitochondrial membrane, and prevents electron transfer from succinate to ubiquinone. This leads to a decrease in production of ATP, which is needed for cell growth and division. N-(5-Nitro-thiazol-2-yl)-benzamide has been shown to inhibit inflammation by inhibiting prostaglandin synthesis in mice. The drug also inhibits neutrophil infiltration into inflamed areas, which may be due to its effect on 5HT2A receptors.
Chemical properties
Technical inquiry about: 3D-PCA39884 N-(5-Nitro-thiazol-2-yl)-benzamide
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