Product Information
- 3-Chloro-β-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]benzenepropanamide
- Benzenepropanamide, 3-chloro-β-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-5-yl]-
- Benzenepropanamide, 3-chloro-β-methyl-N-[2-(4-thiazolyl)-1H-benzimidazol-6-yl]-
- 3-(3-Chlorophenyl)-N-[2-(thiazol-4-yl)-1H-benzimidazol-5-yl]butyramide
Kv2-IN-A1 is a potent and selective inhibitor of the voltage-gated ion channel Kv2.1 (Kv2.1), which is expressed in tissues such as the pancreas, heart, and skeletal muscle. It has been shown to inhibit amide phosphatases and their ability to dephosphorylate membrane proteins. This inhibition leads to an increase in the activity of voltage-gated ion channels, resulting in an increase in membrane excitability and cell function. Kv2-IN-A1 has been shown to be effective at inhibiting voltage-gated ion channels Kv2.1 in vitro and in vivo, with no significant effects on other types of channels.
Chemical properties
Technical inquiry about: 3D-PCB29768 Kv2-IN-A1
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