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Product Information
- ProinsulinC-peptide (human), N-L-tyrosyl-
- Proinsulin connecting peptide (human),1-de-L-arginine-2-L-tyrosine-34-de-L-lysine-35-de-L-arginine-
- 304: PN: US20090175821 SEQID: 378claimed protein
- Proinsulin C-peptide [tyrosyl] (human)
- L-Glutamine,L-tyrosyl-L-a-glutamyl-L-alanyl-L-a-glutamyl-L-a-aspartyl-L-leucyl-L-glutaminyl-L-valylglycyl-L-glutaminyl-L-valyl-L-a-glutamyl-L-leucylglycylglycylglycyl-L-prolylglycyl-L-alanylglycyl-L-seryl-L-leucyl-L-glutaminyl-L-prolyl-L-leucyl-L-alanyl-L
This product is a C-peptide derivative for use in radioimmunoassays. C-peptide is a peptide hormone that is cleaved from proinsulin in the pancreatic beta cells. During glycaemia C-peptide alongside insulin are released by the beta cells. Interestingly C-peptide is not immediately metabolised by the liver and it also has a relatively long half life compared to insulin. Therefore it can be a useful biomarker to monitor beta cell function. Increased levels of C-peptide occurring in patients with insulin resistant type 2 diabetes mellitus, have been associated with macrovascular complications and cardiovascular morbidity. Furthermore C-peptide has been found to prevent endothelial cell reactive oxygen species from being formed thus reducing oxidative stress. This also may lead to anti-inflammatory and anti-apoptotic responses.
Chemical properties
Technical inquiry about: 3D-PCP-3724-PI [Tyr0]-C-Peptide (Human)
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