Atuveciclib (BAY-1143572)
CAS: 1414943-88-6
Ref. 3D-PGC94388
| 1mg | To inquire | |
| 5mg | To inquire | |
| 10mg | To inquire | |
| 25mg | To inquire | |
| 50mg | To inquire |
Product Information
Atuveciclib is a selective inhibitor of CDK4 and CDK6 that has been shown to inhibit the growth of cancer cells in vitro. It was also shown to be effective in vivo, reducing the size of tumors in mice with bowel disease. Atuveciclib has been shown to inhibit lymphoproliferative disorders by targeting the mcl-1 protein, which is essential for cell survival. This drug inhibits the production of inflammatory cytokines such as IL-2, IL-3 and erythropoietin, which are responsible for the development of lymphoproliferative disorders. Atuveciclib has a short detection time and pharmacokinetic properties that enable it to be administered intravenously or orally. It also shows selectivity for kinases over other proteins, making it an attractive potential treatment for inflammatory bowel disease or cancer.
Chemical properties
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