Hepcidin (Rat)
Ref. 3D-PLP-4467-V
| 50µg | 338.00 € |
Product Information
- Asp-Thr-Asn-Phe-Pro-Ile-Cys-Leu-Phe-Cys-Cys-Lys-Cys-Cys-Lys-Asn-Ser-Ser-Cys-Gly-Leu-Cys-Cys-Ile-Thr
Synthetic product of the Hepcidin peptide hormone. Hepcidin in rats is a peptide hormone that plays a key role in the regulation of iron metabolism in the body. Like hepcidin in humans and other mammals, rat hepcidin is produced by the liver and secreted into the bloodstream, where it interacts with other proteins to control the uptake, storage, and distribution of iron.
Rat hepcidin is structurally similar to human hepcidin, with 88% sequence identity. It shares many of the same functional properties as human hepcidin, including the ability to bind to ferroportin, a protein that facilitates the export of iron from cells into the bloodstream, and to inhibit its activity.
In rats, hepcidin expression is regulated by a variety of factors, including iron status, inflammation, and erythropoietic signals. Studies in rats have shown that alterations in hepcidin levels can lead to changes in iron metabolism and the development of iron-related disorders, such as anemia and iron overload.
This product may be useful for the study of hepcidin biology and the regulation of iron metabolism in mammals. It can also provided valuable insights into the mechanisms of iron homeostasis and the development of iron-related diseases in humans.
Chemical properties
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